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Trisomy 12 by FISH

TEST DIRECTORY

Test Name

Trisomy 12 by FISH

Description

Fluorescence in-situ hybridization (FISH) using a DNA probe to detect trisomy of chromosome 12 associated with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL).

Test Code

18743

SPECIMEN REQUIREMENTS

Specimen

Formalin-fixed paraffin embedded tissue, bone marrow, neoplastic blood

Specimen Requirements

Formalin-fixed paraffin embedded tissue, bone marrow or peripheral blood collected in sodium heparin (green topped) tube

Storage Requirements

Store specimens at room temperature (15 to 30°C) until transported, adding a cold (refrigerator) pack during the summer months.

Causes for Rejections

Decalcified tissues are not accepted.

GENERAL AND TECHNICAL INFORMATION

Turn Around Time

Formalin-fixed paraffin embedded tissue: 7 days

Fresh tissue, bone marrow, and blood: 3-10 days

Methodology

Fluorescence in-situ hybridization (FISH)

CPT Code

Formalin-fixed paraffin embedded tissue: 88377
Fresh tissue: 88271, 88275, 88291