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KMT2A Translocation/Deletion by FISH

TEST DIRECTORY

Test Name

KMT2A Translocation/Deletion by FISH

Alternate Names

MLL, 11q23

Description

Fluorescence in-situ hybridization (FISH) using a DNA probe set to detect rearrangements of the KMT2A gene associated with myeloid, lymphoid, or mixed lineage leukemia.

Test Code

89391

SPECIMEN REQUIREMENTS

Specimen

Bone marrow, neoplastic blood, tumor, effusion

Specimen Requirements

Bone marrow or peripheral blood collected in sodium heparin (green topped) tube

Storage Requirements

Store specimens at room temperature (15 to 30°C) until transported, adding a cold (refrigerator) pack during the summer months.

Causes for Rejections

Decalcified tissues are not accepted.

GENERAL AND TECHNICAL INFORMATION

Turn Around Time

Fresh tissue, bone marrow, and blood: 3-10 days

Methodology

Fluorescence in-situ hybridization (FISH)

CPT Code

Fresh tissue: 88271x2, 88275, 88291