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AML/MDS FISH Panel


TEST DIRECTORY
Test Name
AML/MDS FISH Panel
Alternate Names
  • 5q13.1/5q31
  • 7q22.1/7q31
  • t(8;21)
  • 11q23
  • t(15;17)
  • inv(16)
  • 17p13.1
  • 20q13.1
Description
Fluorescence in-situ hybridization (FISH) using 8 DNA probe sets to detect rearrangements, deletions and copy number changes associated with acute myeloid leukemia and myelodysplastic syndromes, consisting of the following:
  • 5q13.1/5q31
  • 7q22.1/7q31
  • t(8;21)
  • 11q23
  • t(15;17)
  • inv(16)
  • 17p13.1
  • 20q13.1
Test Code
87855
SPECIMEN REQUIREMENTS
Specimen
Bone marrow, neoplastic blood
Specimen Requirements
Bone marrow or peripheral blood collected in sodium heparin (green topped) tube
Storage Requirements
Store specimens at room temperature (15 to 30°C) until transported, adding a cold (refrigerator) pack during the summer months.
Causes for Rejections
Decalcified tissues are not accepted.
GENERAL AND TECHNICAL INFORMATION
Turn Around Time
Fresh tissue, bone marrow, and blood: 3-10 days
Methodology
Fluorescence in-situ hybridization (FISH)
CPT Code
88271x14, 88275x8, 88291