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EGFR Mutation Analysis


TEST DIRECTORY
Test Name
EGFR Mutation Analysis
Preauthorization
Third party preauthorization required. Click here for details.
Alternate Names
epidermal growth factor receptor
Description
Only lung primary specimens are accepted. Detection of mutations in exons 18, 19, 20, and 21 of the EGFR gene. Mutations detected include T790M, G719A, G719C, G719S, L861Q, and L858R.
Test Code
778
SPECIMEN REQUIREMENTS
Specimen
FFPE tissue
Storage Requirements
Store specimens at room temperature (15 to 30°C) until transported. DO NOT freeze.
Causes for Rejections
GENERAL AND TECHNICAL INFORMATION
Turn Around Time
7 days
Methodology
Multiplex PCR of exons 19 and 20, followed by sizing of the PCR products by capillary electrophoresis in conjunction with multiplex PCR amplification of EGFR exons 18, 20, and 21, followed by single nucleotide primer extension.
CPT Code
81235, 88381