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BRAF by FISH

TEST DIRECTORY

Test Name

BRAF by FISH

Description

Fluorescence in-situ hybridization (FISH) using a DNA probe set to identify rearrangements of BRAF including BRAF/KIAA1549 fusion associated with pilocytic astrocytomas and low-grade gliomas. This probe set can also detect any other BRAF rearrangement partners (e.g., Spitz tumor, acinar-type neoplasms, etc.).

Test Code

302

SPECIMEN REQUIREMENTS

Specimen

Formalin-fixed paraffin embedded tissue

Specimen Requirements

Formalin-fixed paraffin embedded tissue, 4 unstained slides cut at 4 microns

Storage Requirements

Store specimens at room temperature (15 to 30°C) until transported, adding a cold (refrigerator) pack during the summer months.

Causes for Rejections

Decalcified tissues are not accepted.

GENERAL AND TECHNICAL INFORMATION

Turn Around Time

7 days

Methodology

Fluorescence in-situ hybridization (FISH)

CPT Code

88377