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BRAF by FISH


TEST DIRECTORY
Test Name
BRAF by FISH
Description
Fluorescence in-situ hybridization (FISH) using a DNA probe set to identify rearrangements of BRAF including BRAF/KIAA1549 fusion associated with pilocytic astrocytomas and low-grade gliomas. This probe set can also detect any other BRAF rearrangement partners (e.g., Spitz tumor, acinar-type neoplasms, etc.).
SPECIMEN REQUIREMENTS
Specimen
Formalin-fixed paraffin embedded tissue
Specimen Requirements
Formalin-fixed paraffin embedded tissue, 4 unstained slides cut at 4 microns
Storage Requirements
Store specimens at room temperature (15 to 30°C) until transported, adding a cold (refrigerator) pack during the summer months.
Causes for Rejections
Decalcified tissues are not accepted.
GENERAL AND TECHNICAL INFORMATION
Turn Around Time
Formalin-fixed paraffin embedded tissue: 7 days
Methodology
Fluorescence in-situ hybridization (FISH)
CPT Code
88377