Cytopathologic evaluation for the detection and characterization of inflammatory or infectious processes of the skin, especially herpetic lesions.
Supplies for Submission
No. 2 pencil
Label slides with patient’s full first and last name, using a pencil.
Write "Tzanck Specimen" and the source on the requisition.
Remove crust or dome from lesion and clean away exudate.
Moisten the slide with ethanol just prior to collection.
Scrape margins or denuded base of lesion with curette (not cotton-tipped applicator). For lesions of dry surfaces, such as skin and vulva, it is helpful to moisten the lesion with saline before scraping it.
Quickly spread material on the ethanol-moistened slide.
Spray-fix the specimen with cytology fixative immediately.
Store specimens at room temperature (15 to 30°C) until transported. DO NOT freeze.